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Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover

Metabolism of the hepatic low-density lipoprotein receptor (LDLR) is a key determinant of cholestero...

SCIENCE June 24, 2026

Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover

Metabolism of the hepatic low-density lipoprotein receptor (LDLR) is a key determinant of cholesterol homeostasis1,2. The molecular switches that coordinate...

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Metabolism of the hepatic low-density lipoprotein receptor (LDLR) is a key determinant of cholesterol homeostasis1,2. The molecular switches that coordinate...

Author: Nature

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RAW: FILE: SCIENTISTS WANT TO DIAL DOWN EFFECTS OF EL NINOS

RAW: FILE: SCIENTISTS WANT TO DIAL DOWN EFFECTS OF EL NINOS

There was an issue during media playback with the content that was playing. The sub-error code will contain additional information about the underlying...

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RAW: FILE: SCIENTISTS WANT TO DIAL DOWN EFFECTS OF EL NINOS

RAW: FILE: SCIENTISTS WANT TO DIAL DOWN EFFECTS OF EL NINOS