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αKG-mediated carnitine synthesis drives DNA repair via histone acetylation

Homologous recombination (HR) deficiency increases sensitivity to DNA-damaging agents that are commo...

SCIENCE May 27, 2026

αKG-mediated carnitine synthesis drives DNA repair via histone acetylation

Homologous recombination (HR) deficiency increases sensitivity to DNA-damaging agents that are commonly used to treat cancer1. In HR-proficient cancers,...

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Homologous recombination (HR) deficiency increases sensitivity to DNA-damaging agents that are commonly used to treat cancer1. In HR-proficient cancers,...

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