NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently orien...
SCIENCE
April 13, 2026
De novo formation of cis -regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion
NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently oriented CTCF sites, forming structural loops.
NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently oriented CTCF sites, forming structural loops.
Author: Nature
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